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ProbiFlora™ Legals

ProbiFlora™ Adult Intensive Rescue. Each capsule contains total probiotics 5 billion cfu (colony forming units), probiotic blend consisting of Lactobacillus acidophilus NCFM®, Bifidobacterium lactis HN019, Bifidobacterium lactis BI-04, Lactobacillus rhamnosus HN001, Lactobacillus casei Lc-11, Lactobacillus plantarum Lp-115, Lactococcus lactis LI-23, Bifidobacterium longum BI-05, Streptococcus thermophilis St-21 and prebiotic: prebiotic FOS fibre 50 mg. ProbiFlora™ Adult Classic Bowel Support. Each capsule contains total probiotics 5 billion cfu (colony forming units), probiotic blend consisting of Lactobacillus acidophilus NCFM®, Bifidobacterium lactis BI-07, Lactobacillus casei Lc-11, Lactococcus lactis LI-23 and prebiotic: prebiotic FOS fibre 50 mg. ProbiFlora™ Adult Everyday Flora Balance. Each capsule contains total probiotics 1 billion cfu (colony forming units), probiotic blend consisting of Lactobacillus rhamnosus Lr-32, Bifidobacterium longum BI-05 and prebiotic: prebiotic FOS fibre (Actilight™) 100 mg. ProbiFlora™ Rx. Each capsule contains total probiotics 1 billion cfu (colony forming units), probiotic blend consisting of Lactobacillus rhamnosus Lr-32, Bifidobacterium longum BI-05 and prebiotic: prebiotic FOS fibre (Actilight™) 100 mg. ProbiFlora™ Junior Everyday Flora Balance. Each tablet contains total probiotics 1 billion cfu (colony forming units), probiotic blend consisting of Lactobacillus helveticus R-52ME, Lactobacillus rhamnosus R-11ME, Bifidobacterium longum R-175M. ProbiFlora™ Probiotic Infant Drops 3 strain-Regular drops. Each dose per 4 drops (0,167 ml) contains Bifidobacterium lactis 400 million CFU; Lactobacillus rhamnosus 300 Million CFU; Lactobacillus salivarius 300 million CFU. Health supplement. This unregistered medicine has not been evaluated by the South African Health Products Regulatory Authority for quality, safety or intended use. Adcock Ingram Limited (Pty) Ltd. Reg. No. 1949/034385/06. Private Bag X69, Bryanston, 2021, South Africa. Tel. +27 11 635 0000 www.adcock.com
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* Claims refers to all ProbiFlora™ package inserts.

Website References

1. Rinninella, E., Raoul, P., Cintoni, M., et al. What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases. Microorganisms 2019;7(14):1-22.
2. Wang, H., Wei, C-X., Min, L., et al. Good or bad: gut bacteria in human health and diseases. Biotechnology & Biotechnological equipment 2018;32(5):1075–1080.
3. Nielsen Data July 2019.
4. Gill, H.S., and Guarner, F. Probiotics and human health: a clinical perspective. Postgrad Med J 2004;80:516–526.
5. Kechagia, M., Basoulis, D., Konstantopoulou, S., et al. Health Benefits of Probiotics: A Review. ISRN Nutrition, 2013:1-7
6. ProbiFlora™ Rx (Capsule) Package insert.
7. ProbiFlora™ Probiotics Infant Drops 3 strain – Regular (Drops) package insert.
8. ProbiFlora™ Junior Everyday Flora Balance (Tablets) package insert.
9. ProbiFlora™ Adult Intensive Rescue (Capsule) package insert.
10. ProbiFlora™ Adult Everyday Flora Balance (Capsule) package insert.
11. ProbiFlora™ Adult Classic Bowel Support (Capsule) package insert.
12. Dudek-Wicher, R.K., Junka, A., Bartoszewicz, M. The influence of antibiotics and dietary components on gut microbiota. Gastroenterology Rev 2018;13(2):85–92
13. Ihekweazu,F.D., and Versalovic, J. Development of the Pediatric Gut Microbiome:Impact on Health and Disease. Am J Med Sci 2018;356(5):413.
14. Valdes, A.M., Role of the gut microbiota in nutrition and health. BMJ 361:Supp1 36-44.
15. Vitellio, P., Giuseppe, C., Bonfrate, L., et al. Effects of Bifidobacterium longum and Lactobacillus rhamnosus on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study. Nutrients 2019, (11)886:1-15.
16. Conlon, M.A., and Bird, A.R. The Impact of Diet and Lifestyle on Gut Microbiota and Human Health. Nutrients 2015, 7:17-44.
17. Lee HJ, Choi JK , Ryu HS,et al. Therapeutic Modulation of Gut Microbiota in Functional Bowel Disorders. J Neurogastroenterol Motil, 2017; 23(1):9-19.
18. Agamennone, V., , Krul, C., Rijkers, G., et al. A practical guide for probiotics applied to the case of antibiotic-associated diarrhea in The Netherlands. BMC Gastroenterology, 2018;18(103):1-2
19. Yang, I., Corwin, E.J., Brennan, P.A., et al. The infant microbiome: implications for infant health and neurocognitive development. Nurs Res 2016;65(1):76-88.
20. Baby Centre. Colic in babies: what it is, how long it lasts, and what you can do. July 2019. [Online] [Cited 09/09/2019. Available from URL: https://www.babycenter.com/0_colic-symptoms-causesand-
tips-for-soothing-your-baby_77.bc.

ProbiFlora™ 9 Strain Advert References

1. Wang, H., Wei, C-X., Min, L., et al. Good or bad: gut bacteria in human health and diseases. Biotechnology & Biotechnological equipment 2018;32(5):1075–1080.
2. Probiflora™ Adult Intensive Rescue (Capsule) package insert.
3. Azad, AK., Sarker, M., Li, T., et al. Probiotic Species in the Modulation of Gut Microbiota: An Overview. BioMed Research International 2018:1-8
4. Fijan, S. Microorganisms with Claimed Probiotic Properties: An Overview of Recent Literature. Int. J. Environ. Res. Public Health 2014;11:4745-4767.

ProbiFlora™ Infant Advert References

1. Tintore, M., Colome, G., Santas, J., et al. Gut Microbiota Dysbiosis and Role of Probiotics in Infant Colic. Arch Clin Microbiol 2017; 8(4):1-7.
2. Milani, C., Duranti, S., Bottacini, F. et al. The First Microbial Colonizers of the Human Gut: Composition, Activities, and Health Implications of the Infant Gut Microbiota. Microbiology and Molecular Biology Reviews. 2017;8:1-67
3. ProbiFlora™ Probiotics Infant Drops 3 strain – Regular (Drops) package insert.